The Archaeological Museum of Chania is located in the historic suburb of Chalepa, on a plot of land covering 11,526.81 m2, with a total area of approximately 6,000 m2. Its location, averaging 98 m above sea level, offers a magnificent view over much of the city, especially the seafront. The Museum, designed by architect Theofanis Bobotis and partners, is composed of two distinct linear monolithic masses rising from the earth, a symbolic reference to the vestiges of civilisation beneath the surface.

The permanent exhibition of the Archaeological Museum of Chania is set out in three galleries on the ground floor, presenting the archaeological riches of the regional unit of Chania from the first traces of human presence in Chania to the 4th century AD, and a gallery on the upper floor where part of the Konstantinos, Marika and Kyriakos Mitsotakis Collection is exhibited.

The exhibition is enriched with faithful reconstructions of various spaces, visual media, digital presentations, tactile exhibits (copies of ancient objects) accompanied by Braille captions, and an audio guide.

The Temporary Exhibition Gallery and the Museum gift shop are on the ground floor, while the Educational Programme Room, the Amphitheatre and the Café are on the upper floor.

The Franciscan monastery of San Salvatore, that houses the Byzantine and Post-Byzantine Collection of Chania, was built on the west side of the fortress of Chania, in three phases from the 15th century until the late Venetian period (middle of 17th century). The extensive restoration of the church made it possible to identify more clearly the various building phases of the monument, unify the space, and display its austere, uncluttered architectural features to good effect. The original church, which probably dates from the 15th century, was the small domed section on the east side.